FAQ

Have a question about our products? You can find answers to our most commonly asked questions below. If you still have a question, then please get in touch!

The CellMaker

  • What is the difference between the Plus and the Regular, and how do I know which one is the right for me?

    Which bioreactor is right for me?

     

    CellMaker Regular CellMaker Plus
    No sensors fitted on bioreactor Equipped with DO sensor
    Port fitted as standard for OD probe Equipped with pH & OD ports
    Low cost option Allows for automated control & process optimisation
    8L & 50L bioreactors available 8L & 50L bioreactors available
    Ideal for growth of bacteriophage Ideal when high optical densities required
    Ideal when low optical densities required (<5) Used in CellMaker Plus system only
    Can be used in both CellMaker Regular & Plus systems

  • What is the difference between the Plus and the Low Flow Controllers, and how do I know which one is right for me?

    The Low Flow Controller is an adaptation of the Plus Controller. It has all the same functionality, but the air flow rate is set exceptionally low, from 0.2 to 2L per minute. This allows for very gentle mixing preferred by more sensitive cells, such as CHO and Hybridoma cells.

  • Can you provide a GMP package?

    Yes! The CellMaker controller is compliant with CFR21 part 11 instruction. Please contact us for more information.

  • Are your systems FAT/SAT tested?

    Yes, all our systems are shipped with FAT certification, and we perform Installation and Operation Qualification ‘(IQ/OQ)’ on site upon system purchase.

  • What are the working volumes of the CellMaker Enclosure?

    Our 8L Enclosure has a working volume from 1.5L to 8L, and our 50L Enclosure has a working volume from 10L to 50L.

    Using our Dual Regular Controller, you can achieve working volumes up to 100L, as follows:

    2 x 8L Enclosures: up to 16L

    2 x 50L Enclosures: up to 100L

    1 x 8L and 1 x 50L: up to 58L

  • Which Enclosures are compatible with the Dual Regular Controller?

    You can choose from 2 x 8L, 2 x 50L or 1 of each. These run at the same time and you can choose to run the same process or different processes, all managed from the one Controller.

  • Can I have a demonstration of the system?

    Through experience, we have found out that a short demonstration (for a day or two) doesn’t allow the user to experience the full benefits of the CellMaker. In response, we have created a short-term rental system with very attractive pricing options. Find out more here, or contact us for more information.

Applications

  • What applications can the CellMaker be used for?

    The CellMaker can be used for a wide array of cell cultures and fermentations. We work with our clients in their lab to ensure the system is the right fit for their applications and processes.

    At the moment, we have successfully achieved growth of bacteriophage, E. coli and other bacteria, mammalian cells and antibodies.

  • Is the CellMaker suitable for Anerobic Fermentation?

    Yes, please contact us for more information.

  • How do I monitor optical density using the CellMaker?

    Sample and analyse offline using a spectrophotometer at 600nm.

CellMaker Features

  • Which gasses can I use with the CellMaker?

    If your process requires air only, the CellMaker has a built-in air pump making it a completely stand-alone system.

    For processes requiring other gasses, the CellMaker can accept oxygen, carbon dioxide, nitrogen and argon.

  • What process temperature can the CellMaker deliver?

    The CellMaker can easily achieve temperatures from 16°C to 40°C.

    Please contact us to discuss any applications outside of this range.

  • Can you customise the CellMaker?

    Yes! As we build the machines in house, we may be able to customise to your requirements depending on feasibility and cost.

  • Can we have a bigger bioreactor?

    We currently offer an 8L and 50L Enclosure for use with our Controller. Using our Dual Regular Controller, you can run two Enclosures at the same time, increasing your production potential to 100L if run with 2 x 50L Enclosures.

     

    We have an in-house Research and Development team who are always looking for ways to improve the system, and we do plan to grow our range in the future.

  • What accessories are available for the CellMaker?

    We offer peristaltic dosing pumps and reusable/ single-use pH sensors, suitable for use with all of our systems.

  • What are the CellMaker Bioreactor Bags made of?

    The CellMaker Bioreactor Bags are made from an inner and outer layer made from low density polyethylene and an intermediate gas-barrier layer of ethylene vinyl alcohol (EVOH). All bags arrive sterile and ready for use.

Everything else